Leptin is a major player in the war against “rebound weight-gain.” You know…the weight that you worked so hard to take off that is creeping back on.

Studies prove that there is an important connection between the hormone leptin, weight gain and inflammation.

Because leptin regulates your body’s level of fat by controlling your appetite and metabolism, it’s obvious that the more fat tissue you add, the more leptin is produced by your body. For healthy people this process leads to leptin suppressing the appetite but speeding up the metabolism causing them to feel less hunger and burn more calories resulting in loss of excess fat, the way the process is supposed to work.

However, this process does not work properly in those with chronic inflammation because chronic inflammation impairs the brain’s ability to receive leptin’s message to shut down the appetite. [Read more…]